The safety of weight loss pills can vary based on whether they are prescription medications or over-the-counter supplements. Prescription weight loss pills have undergone rigorous testing and are generally considered safe when used under medical supervision. However, they can still have side effects, such as nausea, bowel changes, and increased blood pressure. Over-the-counter weight loss supplements are not as strictly regulated and may pose risks due to unverified ingredients or incorrect dosages. It’s essential to consult with a healthcare professional before starting any weight loss pill, even if they are available without prescription.

Weight loss pills work through different mechanisms, depending on their active ingredients. Here are a few common ways they work:

• Appetite suppressants. These pills help reduce hunger and cravings, making it easier to eat less. They often work by affecting brain chemicals that regulate appetite.
• Fat absorption inhibitors. These medications prevent the absorption of fat from the food you eat, reducing overall calorie intake. Orlistat (Xenical) is a well-known example that works this way.
• Metabolism boosters. Some pills contain ingredients that can help increase your metabolism, allowing your body to burn more calories throughout the day.

The “best” weight loss pills depend on individual needs and medical conditions. Some of the commonly prescribed weight loss medications include:

• Orlistat (Xenical/Alli). Effective at reducing fat absorption.
• Semaglutide (Rybelsus). Helps your body better regulate blood sugar levels and slows the rate at which food passes through your stomach, so you feel fuller for longer; and therefore eat less.

Each of these medications has its pros and cons, and their suitability should be determined by a healthcare professional.

Some of the strongest and most effective prescription weight loss pills include:

• Phentermine-Topiramate (Qsymia). Known for its significant impact on weight loss.
• Liraglutide (Saxenda). A GLP-1 receptor agonist that helps control appetite and is highly effective.
• Semaglutide (Wegovy). Another GLP-1 receptor agonist that has shown remarkable results in clinical trials for weight loss.

These medications are potent and typically only prescribed for individuals with a BMI over 30 or those with a BMI over 27 who have weight-related health issues, such as diabetes or high blood pressure.

The cost of weight loss pills can vary widely:

• Prescription medications. These can range from £50 to £200 per month, depending on the medication and whether it’s covered by private health insurance.
• Over-the-counter supplements. These are generally cheaper, ranging from £10 to £50 per month, but their effectiveness and safety can vary.

Yes, some weight loss pills are available on the NHS, but they are typically prescribed only to individuals who meet specific criteria. For example, Orlistat (Xenical) is available for those with a BMI of 30 or higher, or a BMI of 28 or higher with additional weight-related health conditions like diabetes or hypertension. The NHS may also require a patient to be assessed by a specialist, which often has long wait times.

Yes, a GP can prescribe weight loss pills if you meet the eligibility criteria. For NHS prescriptions, your BMI and any weight-related health conditions will be assessed. If you do not qualify for an NHS prescription or prefer a different medication, you can seek an assessment with a private prescription service. This would involve an additional cost, which can be higher but may provide access to a broader range of medications.