Mounjaro 5mg is typically the first dose that most people progress to after their initial 2.5mg start. It’s an essential part of the titration process and plays a critical role in appetite suppression and weight loss as you get accustomed to the medication. Here’s what you need to know about using 5mg effectively.
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Next Review: Jul 31, 2027
When is 5mg typically prescribed?
The Mounjaro 5mg dose is “step 2” in the titration process.
After successfully adjusting to the initial 2.5mg dose, 5mg is usually introduced to enhance the weight loss process.
At this dose, many patients start to experience noticeable changes in appetite and cravings.
Clinicians may increase the dose to 5mg if you’ve been on 2.5mg for around 4 weeks without significant side effects.
How much does Mounjaro 5mg cost?
A Mounjaro 5mg pen costs £189 (4 weeks).
That’s equivalent to £6.75/day.
You can save £50 on your first order as a new Medicspot patient.
What to expect when you start 5mg
Benefits include:
- Appetite reduction – One of the most noticeable effects at 5mg is a significant decrease in hunger.
- Continued weight loss – Many patients see progressive weight loss after moving to 5mg.
- Improved blood sugar regulation – Even if you’re not diabetic, Mounjaro helps stabilise glucose levels, improving overall metabolic function.
Common side effects include:
- Mild nausea – This is common when your body adjusts to the medication.
- Tiredness or fatigue – A mild feeling of tiredness or low energy in the initial weeks is possible.
- Digestive issues – Some users report bloating, constipation, or mild stomach discomfort.
If you experience nausea on 5mg, try eating smaller, more frequent meals. Avoid heavy or greasy foods, which can exacerbate side effects.
How your body is adapting at 5mg
At this stage:
- GLP-1 and GIP hormones are becoming more active, helping control your appetite and manage insulin sensitivity.
- Reduced gastric emptying time means you’ll feel fuller longer.
- Insulin resistance improvement might already begin, especially if you’re dealing with type 2 diabetes or pre-diabetes.
Patient experiences at 5mg
“Started 5mg 3 weeks ago. Have not had any side effects. Didn’t have any really on 2.5mg either. Some people seemed to have really bad side effects on 5mg. I read so many horrible stories that I was afraid to take it but I’ve been fine.”
“On my 2nd week of 5mg. I have to say that I’ve injected in my arm this week and I’m feeling more suppression than when I did my stomach last week. Don’t know if that’s just psychological..!!”
“I noticed a tailing off of effectiveness of the 2.5 in the third month but the 5 is going well, bar some nausea and tiredness the first couple of days after injection.”
“I took my first 5mg on Monday and have been absolutely fine, if anything I think it’s better because I’m less hungry.”
Is it time to move to 5mg?
It might be time to ask your clinician about moving up to 5mg if:
- you’ve been on 2.5mg for at least 4 weeks
- your appetite suppression fades away before it’s time for your next jab
- your weight loss on 2.5mg has slowed or plateaued
- you are not experiencing any significant side effects
It might be time to ask your clinician about moving down to 5mg if:
- you’re experiencing significant side effects on 7.5mg
- you’re losing weight too fast on 7.5mg
- you have reached your healthy target weight and want to gradually reduce your dose
What not to do at 5mg
- Don’t skip meals – Skipping meals can throw off your blood sugar and exacerbate nausea.
- Don’t rush to increase the dose – Give your body time to adjust – most people stay at 5mg for at least 4 weeks.
- Don’t ignore side effects – If side effects feel unbearable, it’s OK to temporarily lower the dose. Always consult with your clinician.
At 5mg, appetite suppression is strong, but hunger cues can still be tricky. Focus on eating slower and noticing when you feel satisfied rather than full.
Mounjaro 5mg FAQs
More questions about Mounjaro 5mg?
Book a call with our team to discuss any questions you may have about the Mounjaro 5mg dose.